Alice was born about 1500, the daughter of John Syer but her mother is unknown. The place is not known.
Her husband was Richard ap_Eignion, who she married in ABT 1517. The place has not been found. Their ten known children were Adam (c1519-c1561), Robert (c1521-?), Joan (c1523-?), Eleanor (c1524-?), Richard (c1525-?), William (c1529-?), John (c1531-?), Edward (c1533-?), Thomas (c1535-<1588) and Hugh (c1537-?).